Science

Science (from Latin scientia, meaning “knowledge”) is a systematic enterprise that builds and organizes knowledge in the form of testable explanations and predictions about the universe.

don’t mess with a good thing

The oldest known written record of cannabis use comes from the Chinese Emperor Shen Nung in 2727 BC. The early Chinese surgeon Hua Tuo (c. AD 140- 208) is credited with being the first recorded person to use cannabis as an anesthetic. He reduced the plant to powder and mixed it with wine for adminis­tration prior to performing surgery.* In India, Bhang, a drink made with raw cannabis, is considered to be an overall wellness beverage. Steam baths in the Middle East also show evidence of cannabis use to help with inflammation.

17th Century America, farmers in Virginia, Massachusetts and Connecticut were ordered by law to grow Indian hemp. By the early 18th century, a person could be sentenced to jail if they weren’t growing hemp on their land! Hemp was considered to be legal tender. For over 200 years in colonial America, hemp was currency that one could use to pay their taxes with! (Don’t try that today, kids!)

ONE SIZE DOES NOT FIT ALL

Each persons body and endocannabinoid system are unique, with different needs and receptors. We believe your wellness products should be as well.

Cannabinoids are one of the strongest anti-inflammatory agents found in nature, and we know that organic tinctures in combination with the right herbs can provide some of the most incredible results.

We constantly test our products and use leading industry research to demonstrate the efficacy of each formulation for a number of ailments, partnering with domestic & international firms to initiate this work. 

Our physician & scientic advisory board ensure that we have the best minds looking at our products. 

Cannabinoid’s explained

Cannabinoids are the chemical compounds cannabis flowers secrete that provide natural protection to the plant. There are over 80 cannabinoids unique to cannabis.

Cannabinoids closely resemble the natural compounds our own bodies produce, called endocannabinoids. The endocannabinoid system can be thought of as the air traffic control center for the body, as it controls such physiological processes as appetite, pain-sensa­tion, mood, and memory.

Each cannabinoid has a different composition and influence of the receptors in the endocannabinoid system. The different cannabinoids provide the opportunity to successfully treat a wide variety of ailments and to relieve an array of symptoms.

ENDOCANNABINOID SYSTEM

Cannabinoids affect the user by interacting with the CB1 and CB2 receptors located within different parts of the central nervous system. A substance that occurs naturally in the brain and binds to CB1 receptors was discovered in 1992 and termed anandamide. Addition­al naturally occurring substances that bind to CB1 and CB2 receptors have since been discovered, and these, together with the receptors, are termed the endoge­nous cannabinoid system, or endocannabinoid system for short.

CB1 receptors are most abundant in the central ner­vous system, while CB2 receptors are more abundant in the cardiovascular, gastrointestinal, and peripheral nervous systems. Phytocannabinoids are cannabinoids that are produced by plants such as cannabis. They bind to the same CB receptors as endocannabinoids, but they interact with the endocannabinoid system in many different ways. These interactions are what drive modern research into phytocannabinoids and much of the current medical discoveries as  research continues to grow.

The physiological effects of cannabinoids reflect the areas of the brain with which they interact. Interac­tions tend to occur in our limbic system (the part of the brain that affects memory, cognition, and psycho­motor performance) and in our mesolimbic pathway (activity in this region is associated with feelings of reward) and are also widely distributed in areas of pain perception.

BIOAVAILABILITY

Bioavailability refers to the absorption of cannabinoids in the body. This absorption varies by body site and delivery method (i.e., topical, sublingual, ingestion, inhaling). Inhaling 10 mg of a phyto cannabinoid rich product through a vape is not equal to ingesting 10 mg of the same product in a tincture. Some natural compounds, such as coconut oil, absorb rapidly through the skin and metabolize quickly, making them ideal substrates for cannabis topicals and edibles.

So what does all this mean? We have done our research, understand how Hemp’s Oil work in conjuntion with the ECS & the Bioavailibilty of the formualtions we create to deliver maximum results to YOU.

find relief & balance

At BIOLIEF, we believe strongly that chronic inflammation and other conditions such as pain can be relieved through  a balanced holistic approach; we can assist in selecting the best product for you. Consider the following when deciding on the best product:

  1. The ailment/indication you are seeking relief from.
  2. The preferred delivery method.
  3. The potency you want.

DELIVERY METHODS

BIOLIEF offers different delivery systems, with varying cannabinoid ratios to provide customized types and amounts of relief. It is important to un­derstand how the body is processing cannabinoids across these different products. Additionally, there are a number of factors to consider when thinking about various delivery methods, like targeted relief vs. whole body, onset time, psychoactivity, and how long the effects will last. Read more about these methods in the tabs below:

Topicals provide relief through cannabinoids pene­trating the skin (our largest organ) and interacting with our receptors to reduce pain, swelling, and in­flammation. Results can be felt in a few minutes and relief can last anywhere from two to four hours. Fatty tissues can also store CBD to provide ongoing relief. Most importantly, the cannabinoids do not reach the bloodstream, so pain relief is local with no psychoac­tivity. And because the cannabinoids don’t reach the bloodstream, overdosing is not a concern and you can apply as liberally as needed. The more cannabinoids, the more relief, so it is important to take note of can­nabinoid counts on the label.
When taking tinctures, capsules, or edibles orally, the cannabinoids are metabolized in the stomach like a food or beverage. The cannabinoids enter the blood­stream directly and immediately travel to the brain, where they bind to cannabinoid receptor cells. When ingested, THC becomes 11-hydroxy-tetrahydrocan­nabinol, a cannabinoid that is five to ten times more psychoactive than THC itself. CBD, however, can be ingested without any concern for psychoactive effects. For best effect throughout the body, ingesting CBD is one of the best ways to absorb CBD for its strong anti-inflammatory properties. This method has similar mind and body effects to inhaling cannabis through smoking or vaporization. Effects are usually felt within 15 to 45 minutes and last two to three hours.

Vaping allows the user to inhale the cannabinoids from the hemp oil product  and the can­nabinoids go directly into the bloodstream.  The user can experience relief within minutes.

Patches are a transdermal delivery system, meaning that the cannabinoids penetrate all layers of the skin to reach your bloodstream. This affects pain and in­flammation throughout the body, regardless of the pain’s location. Transdermal patches release slowly, so they deliver the full cannabinoid content over the course of 12 hours.

The low doses of cannabinoids do not cause psycho­activity, but they do represent a therapeutic dose of cannabinoids for users suffering from chronic pain and inflammation. Effects are usually felt within 30 to 45 minutes and last for 12 hours.